Nicotinamide Quick Details
Product Name: Nicotinamide
CAS No.: 98-92-0
Nicotinamide formula: C6H6N2O
Nicotinamide Typical Properties
|Appearance||White crystalline powder||Conform|
|Loss on drying||≤0.5%||0.1%|
|Residue on ignition||≤0.1%||Complies|
|Readily carbonizable||≤Matching Fluid A||Complies|
|Conclusion||The Results Conforms With USP36|
1. Nicotinamide can improve the skin barrier function. Ceramide is an important component of the skin barrier. Nicotinamide enhances the skin barrier function and increases the transepidermal water loss by increasing the ceramide content in the stratum corneum.
2. Nicotinamide can control oil and reduce pores. Increased pore size is one of the skin texture problems. Topical nicotinamide can reduce the production of fatty acids and triglycerides in sebum, thereby reducing pores and reducing the severity of acne.
Nicotinamide for skin
Speaking of nicotinamide has to say a component called niacin. Nicotinamide has the best stability in a solution with a pH of 6. In a solution with a pH above or below 6, it will hydrolyze to form niacin, which is a component that will make many people intolerant to niacinamide. When using nicotinamide products, it will become red and hot. Intolerance to the reaction. Therefore, nicotinamide-containing formulations generally control pH between 5 and 7 to reduce niacin formation.
Nicotinamide production method
1. Put niacin, boric acid and ammonia into the reaction pot, add ammonia gas under stirring, and dissolve at elevated temperature; then distill off ammonia to dilute to 120~C and transfer to dehydration pot to continue concentration;
2. When the temperature reaches 145 °C, the liquid ammonia is added, and the ammonia reaction is continued at 185-190 °C for 20-30 hours. Then, the temperature is lowered to 130 ° C, diluted with distilled water, activated carbon, and decolorized by ammonia at 70-80 ° C for 2 h;
3. After the reaction, the mixture was filtered while hot, and the filtrate was subjected to cold analysis in water for 24 hours, and the crystals were separated and washed with ethanol and dried to give a yield of 89%.
Nicotinamide Packaging and Shipping
25kg per fiber drum,polyethylene bag liner inside,barrel head lead sealing with iron ring.
Be stored in cool, dry, and ventilated storage, free from heat or sunlight and free from toxic and harmful foods. Be protected with pall on delivery, keep free from rain moisture, toxic, and harmful goods. Shelf life 3 years.